GAO Shutao,XU Tao,MAIERDAN Maimaiti.Clinical efficacy of posterior approach release and reduction of lateral mass joint followed by bone grafting and occipital-cervical internal fixation for basilar invagination with irreducible atlantoaxial dislocation[J].Chinese Journal of Spine and Spinal Cord,2023,(10):865-871.
Clinical efficacy of posterior approach release and reduction of lateral mass joint followed by bone grafting and occipital-cervical internal fixation for basilar invagination with irreducible atlantoaxial dislocation
Received:March 15, 2023  Revised:September 23, 2023
English Keywords:Basilar invagination  Irreducible atlantoaxial dislocation  Interbody fusion cage  Lateral mass joint bone graft and fusion
Fund:国家自然科学基金项目(编号:81960235;82360257)
Author NameAffiliation
GAO Shutao Department of Spine Surgery, the First Affiliated Hospital of Xinjiang Medical University, Urmuqi, 830054, China 
XU Tao 新疆医科大学第一附属医院脊柱外科 830054 乌鲁木齐市 
MAIERDAN Maimaiti 新疆医科大学第一附属医院脊柱外科 830054 乌鲁木齐市 
郭海龙  
甫拉提·买买提  
盛 军  
荀传辉  
王 婷  
盛伟斌  
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English Abstract:
  【Abstract】 Objectives: To evaluate the clinical outcomes for the treatment of basilar invagination(BI) with irreducible atlantoaxial dislocation(irAAD) through posterior approach release and reduction of lateral mass joint followed by bone grafting and occipital-cervical internal fixation. Methods: The clinical data of patients of BI-irAAD undergone posterior approach release and reduction of lateral mass joint followed by bone grafting and occipital-cervical internal fixation at our institution between January 2010 and January 2020 were retrospectively analyzed. A total of 19 patients were enrolled, including 11 males and 8 females. The average age of the patients was 37.4±13.9 years(range 13-69 years), and the follow-up period was 54.7±29.4 months(25-131 months). Visual analogue scale(VAS) and Japanese Orthopaedic Association(JOA) scores before operation, at postoperative 1 week, six month and final follow-up were recorded to evaluate the relief of neck pain and the recovery of neurological functions, respectively. The atlantodental interval(ADI), distance of the top of odontoid to Chamberlain′s line(DOCL), and cervico-medullary angle(CMA) before operation, at postoperative 1 week and final follow-up were measured on cervical midsagittal CT and MRI. The bony fusion condition was evaluated on CT and complications were also recorded. Results: The operative time was 136.1±29.0min(range 95-210min) and blood loss was 189.7±85.0mL(range 100-455mL). For functional scores, the VAS was 6.06±1.21 points preoperatively, 2.35±0.76 points at one week postoperatively, 1.24±0.81 points at six months of follow-up, and 1.12±0.90 points at the final follow-up. The JOA was 9.26±2.24 points preoperatively, 14.05±2.01 points at one week postoperatively, 15.05±1.57 points at six months of follow-up, and 15.16±1.42 points at the final follow-up. The VAS and JOA at one week postoperatively, six months of follow-up, and final follow-up significantly improved than those before operation(P<0.05). Regarding dislocation, the ADI was 9.63±1.93mm preoperatively, 1.21±1.10 mm at one week postoperatively, 1.16±1.09mm at six months of follow-up, and 1.26±1.02mm at the final follow-up. The DOCL was 11.47±3.93mm preoperatively, 2.53±3.30mm at one week postoperatively, 2.32±3.20mm at six months of follow-up, and 2.26±2.73 mm at the final follow-up. The CMA was 114.31°±11.00° preoperatively, 144.16°±9.33° at one week postoperatively, 145.31°±8.83° at six months of follow-up, and 143.42°±9.12° at the final follow-up(P<0.05). The ADI, DOCL and CMA at one week postoperatively, six months of follow-up, and final follow-up significantly improved than those before operation(P<0.05). Bony fusion was achieved in all patients, the fusion duration was 10.3±2.7 months(range 5-15 months). Of these patients, one developed wound infection and one developed cerebrospinal fluid leakage. The two patients were cured through corresponding management. No patient developed implant failure or re-dislocation. Conclusions: Posterior approach release and reduction of lateral mass joint followed by bone grafting and occipital-cervical internal fixation is a safe and efficient surgical strategy for the treatment of BI-irrAAD.
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