XIA Tian,SUN Yu,PAN Shengfa.Radiological features and treatment strategy of multilevel cervical disconnection syndrome[J].Chinese Journal of Spine and Spinal Cord,2021,(12):1072-1077, 1105.
Radiological features and treatment strategy of multilevel cervical disconnection syndrome
Received:October 09, 2021  Revised:December 27, 2021
English Keywords:Severe congenital cervical kyphosis  Pre-correction by traction  Multilevel cervical disconnection syndrome
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Author NameAffiliation
XIA Tian Department of Orthopaedics, Peking University Third Hospital, Beijing Key Laboratory of Spinal Disease Research, Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing, 100191, China 
SUN Yu 北京大学第三医院骨科 脊柱疾病研究北京市重点实验室 骨与关节精准医学教育部工程中心 100191 北京市 
PAN Shengfa 北京大学第三医院骨科 脊柱疾病研究北京市重点实验室 骨与关节精准医学教育部工程中心 100191 北京市 
周非非  
刁垠泽  
陈 欣  
赵衍斌  
张凤山  
张 立  
王少波  
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English Abstract:
  【Abstract】 Objectives: To analyze and discuss the radiological manifestation and surgical treatment strategy of multilevel cervical disconnection syndrome(MCDS). Methods: Between March 2004 and June 2021, 7 patients with MCDS were treated in our institute. There were 3 males and 4 females, aging from 5 to 46 years old(median: 12 years old). Among them, dysplasia of vertebral body averaged 3.6±1.3 levels and segments with anterior-posterior disconnection averaged 5.7±1.5 levels. The mean local kyphotic angle was -92.2°±20.2°, mean C2-7 Cobb angle was -68.6°±31.0°, mean T1 slope(T1S) was -12.5°±12.5°. The apex was located at C4 in 1 patient, C5 in 5 patients, and T1 in 1 patient. The mJOA score ranged from 8.5 points to 14 points(average: 12.6±2.1 points), with 1 patient accompanied by dysphagia. The methods and techniques for pre-correction and surgical treatment, radiological parameters when admitted, instant after surgery and during the final follow-up, and the neurological functions and perioperative complications were recorded. Results: For preoperative correction, one patient received skull traction, three received suspensory correction, and three received combined traction. The correction rate was 60.8%. The average fusion level was 6.0±2.1 levels. One patient received anterior soft-tissue release combined with Halo-vest, one received anterior correction and fusion, one received posterior correction and fusion, and 4 received anterior-posterior combined approach. Two patients encountered neurological complication and received revision surgery. The follow-up period ranged from 6 to 84 months(mean: 41.2±32.0 months). During the final follow-up, the mean local kyphotic angle was -27.9°±11.6°, correction rate was 69.7%, mean C2-7 Cobb angle was -13.3°±28.4°, mean T1S was 4.9°±17.9°. mJOA score ranged from 10.5 to 17 points(15.7±2.3 points), and the recovery rate was 78.3%. Comparing the clinical and radiological parameters before and after operation, the mJOA score, C2-7 Cobb angle, local kyphotic angle, and T1 slope were with significant differences. Conclusions: The radiological features of MCDS were dysplasia of vertebral body and multilevel disconnection of pedicle, causing severe kyphotic deformity. Initial treatment should be pre-correction by traction. Surgical treatment should include anterior multilevel corpectomy and correction, combined with posterior long segment fusion.
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