SUN Xiangyao,LU Shibao,ZHANG Qingming.The risk factor analysis of kyphosis reccurrence in single level thoracolumbar burst fracture after short-segment instrumentation in fractured vertebra[J].Chinese Journal of Spine and Spinal Cord,2018,(8):690-697.
The risk factor analysis of kyphosis reccurrence in single level thoracolumbar burst fracture after short-segment instrumentation in fractured vertebra
Received:March 29, 2018  Revised:June 24, 2018
English Keywords:Thoracolumbar fracture  Burst fracture  Internal fixation  Kyphosis reccurrence  Risk factor
Fund:国家自然科学基金面上项目(81672201);首都卫生发展科研课题(首发2014-2-2032);北京市卫生和计划生育委员会“老年重大疾病关键技术研究”(PXM2017 026283 000002)
Author NameAffiliation
SUN Xiangyao Department of Orthopedics, Xuanwu Hospital Capital Medical University, Beijing, 100053, China 
LU Shibao 首都医科大学宣武医院骨科 国家老年疾病临床医学研究中心 100053 北京市 
ZHANG Qingming 首都医科大学宣武医院骨科 国家老年疾病临床医学研究中心 100053 北京市 
孔 超  
海 涌  
洪 毅  
李 放  
陈学明  
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English Abstract:
  【Abstract】 Objectives: To analyze the risk factors of kyphosis reccurrence in thoracolumbar burst fracture before or after implant removal after short-segment instrumentation in fractured vertebra. Methods: From January 2014 to January 2016, patients with thoracolumbar burst fracture who underwent posterior short-segment pedicle screw instrumentation in the cooperation units were carefully reviewed. The followings were obtained: age, Cobb angle of the fractured segment(CA), regional angle(RA), vertebral wedge angle(VWA), anterior vertebra height ratio(AVH), posterior vertebra height ratio(PVH), anteroposterior ratio(A/P), upper intervertebral angle(UIVA), lower intervertebral angle(LIVA), body mass index(BMI), visual analogue scale(VAS), thoracolumbar injury classification and severity score(TLICS), load-sharing classification(LSC), history of diabetes. Posterior kyphosis reccurrence was defined as posterior correction loss >10°. The patients were divided into kyphosis recurrence(KR) group and none kyphosis recurrence(NKR) group. The parameters were analyzed according to before or after implant removal. Logistic regression was used to analyze the risk factors. The threshold value was calculated by ROC curve analysis. Results: A total of 196 patients from 5 cooperation units were included in this study. When KR group was compared with NKR group before implant removal, age(P<0.001) and BMI(P<0.001) were risk factors of kyphosis reccurrence; age >58.5 years[area under curve(AUC)=0.885], BMI >29.1kg/m2(AUC=0.962) were the thresholds. When KR group was compared with NKR group after implant removal, female(P<0.001), age(P<0.001), BMI(P<0.001), L1 fracture(P<0.001), AO classification of A3.3(P=0.001), preoperative UIVA(P=0.014) were the risk factors of kyphosis reccurrence after implant removal; T12 fracture(P<0.001), AO classification of A3.1(P<0.001), preoperative AVH(P<0.001) were the protective factors; age >50.5 years(AUC=0.789), BMI >26.6kg/m2(AUC=0.740), preoperative UIVA >-4.2°(AUC=0.650), preoperative AVH >60.5% were the thresholds. Conclusions: Before implant removal, age >58.5 years and BMI >29.1kg/m2 are the risk factors of kyphosis reoccurrence in single level thoracolumbar burst fracture after short-segment instrumentation. After implant removal, age >50.5 years(AUC=0.789), BMI >26.6kg/m2(AUC=0.740), preoperative UIVA >-4.2°(AUC=0.650), L1 fracture, AO classification of A3.3 are the risk factors of kyphosis reoccurrence; T12 fracture, AO classification of A3.1 and preoperative AVH >60.5% are the protective factors of kyphosis reccurrence.
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