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LI Ning,WANG Jie,LUO Ming.Comparison of abnormal vertebral pedicles between dystrophic and nondystrophic scoliosis in neurofibromatosis type 1[J].Chinese Journal of Spine and Spinal Cord,2018,(5):434-439.

Comparison of abnormal vertebral pedicles between dystrophic and nondystrophic scoliosis in neurofibromatosis type 1

Received:January 22, 2018 Revised:April 24, 2018

English Keywords:Abnormal pedicles Neurofibromatosis type 1 Scoliosis Dystrophic Nondystrophic

Fund:河南省基础与前沿技术研究计划项目资助（142300410379）；河南省国际科技合作计划项目资助（152102410062）

Author Name	Affiliation
LI Ning	The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China
WANG Jie	郑州大学第一附属医院骨科 450052 郑州市
LUO Ming	郑州大学第一附属医院骨科 450052 郑州市
申明奎
白玉
刘磊
夏磊

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English Abstract:

【Abstract】 Objectives: To explore the prevalence of abnormal vertebral pedicles in neurofibromatosis type 1 (NF1-S), and to compare the difference between dystrophic and nondystrophic scoliosis. Methods: Based on computed tomography images, vertebral pedicles from 30 patients with NF1-S with dystrophic scoliosis and 30 patients with NF1-S with nondystrophic scoliosis were carefully measured. Pedicle morphology was classified into five types: type A, cancellous channel >4mm; type B, cancellous channel from 2mm to 4mm; type C, cancellous channel <2mm with entirely cortical channel ≥2mm; type D, cortical channel <2mm; type E, absent pedicle. Type B, C, D and E were defined as abnormal. The incidence of anomalous pedicles in different NF1-S patients and their distribution in the area of lateral convex arc were compared. Results: The total prevalence of abnormal pedicles in patients with NF1-S was 67.5%(1376/2040), including type B 39.6%(807/2040), type C 22.3%(455/2040), type D 3.6%(74/2040) and type E 2.0%(40/2040). The prevalence of abnormal pedicles in the arc region was as high as 75.3%(975/1294), which accounted for 70.9% of total abnormal pedicles(975/1376). The prevalence of abnormal pedicles of dystrophic scoliosis was much higher than that of nondystrophic scoliosis(72.3% vs. 62.6%, P<0.05). Conclusions: Abnormal pedicles in patients with NF1-S mainly concentrate in the arc region. The prevalence of abnormal pedicles of dystrophic scoliosis is significantly higher than that of nondystrophic ones.

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