TANG Yongchao,MO Guoye,ZHANG Shuncong,.Mid-to-long term efficacy analysis of percutaneous vertebral augamentation applied on the Kümmell′s disease without neurological deficit[J].Chinese Journal of Spine and Spinal Cord,2018,(1):38-43.
Mid-to-long term efficacy analysis of percutaneous vertebral augamentation applied on the Kümmell′s disease without neurological deficit
Received:October 19, 2017  Revised:November 20, 2017
English Keywords:Kümmell disease  Percutaneous vertebral augmentation  Osteoporosis
Fund:广东省科技厅课题资助项目(编号:2016A020215137)
Author NameAffiliation
TANG Yongchao First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China 
MO Guoye 广州中医药大学第一临床医学院 510405 广州市 
ZHANG Shuncong, 广州中医药大学第一附属医院脊柱专科 510405 广州市 
梁 德  
郭丹青  
李永贤  
杨志东  
江晓兵  
李大星  
郭惠智  
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English Abstract:
  【Abstract】 Objectives: To evaluate the mid-long term efficacy and safety of percutaneous vertebral augmentation(PVA) applied on the Kümmell′s disease without neurological deficit. Methods: From June 2009 to June 2013, 32 patients(4 males and 28 females, 69.95±7.72 years old on average) with Kümmell′s disease of non-neurological deficit receiving percutaneous vertebral augmentation were reviewed. The average T score of bone mineral density was -3.43±0.22SD. The radiological variations including the Cobb angle, anterior and middle height of index vertebra and the type of bone-cement distribution obtained from X-ray were recorded preoperatively, at 3 days postoperatively and the final follow-up. Meanwhile, the visual analogue scale(VAS) and Oswestry disability index(ODI) scores were also evaluated. Results: The average follow-up time was 2.81±0.97 years(2-6 years). 7 cases were observed with asymptomatic bone-cement leakage. The vertebral height and the Cobb angle significantly improved after operation(P<0.05), however, aggravated at the final follow-up(P<0.05). The ODI and VAS scores decreased significantly after operation(P<0.05), but increased a little without significant difference at the final follow-up compared with those at 3 days postoperatively. In addition, three types of morphological changes of bone-cement vertebrae were detected: (1)spontaneous fusion with adjacent vertebrae occurring in all cases; (2)cement fragmentation or migration found in 6 cases; (3)bright lines found in 8 cases. Conclusions: PVA in treatment of the Kümmell′s disease without neurological deficit abtains a significant short-term efficacy. However, PVA is unable to provide adequate stability in mid-long term follow-up,due to the height loss and kyphosis of the index vertebra aggravating. Close follow-up is mandatory.
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