ZHENG Xiaoqing,GU Honglin,LIANG Guoyan.Clinical outcomes of oblique lumber interbody fusion in lumbar degenerative disease[J].Chinese Journal of Spine and Spinal Cord,2017,(9):817-822.
Clinical outcomes of oblique lumber interbody fusion in lumbar degenerative disease
Received:June 20, 2017  Revised:August 13, 2017
English Keywords:Oblique lumber interbody fusion  Lumbar degenerative disease  Clinical outcome
Fund:广东省省级科技计划项目(编号:2014A020212402)
Author NameAffiliation
ZHENG Xiaoqing Division of Orthopedic Surgery, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China 
GU Honglin 广东省人民医院骨科 510000 广州市 
LIANG Guoyan 广东省人民医院骨科 510000 广州市 
庄见雄  
尹 东  
刘 斌  
昌耘冰  
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English Abstract:
  【Abstract】 Objectives: To analyze the clinical outcomes of oblique lumber interbody fusion(OLIF) in treating lumbar degenerative disease. Methods: 24 cases were selected who had lumbar degenerative disease and treated with oblique lumber interbody fusion between October 2015 and May 2016. The operations were performed in 36 segments of 8 males and 16 females, with an average age of 62.3±12.0(range, 44-88) years old. Lumbar function was evaluated according to Japanese Orthopaedic Association(JOA) score and Oswestry disability index(ODI). The intervertebral disc height(IDH) and intervertebral foramen height(IFH) were measured on lumbar plane X-ray before surgery, 1 week after surgery and at final follow-up after operation. The operation time, blood loss and postoperative complication were observed, and then the causes were analyzed. Results: The mean operation time was 135±21.0 minutes(100-170 minutes); and the mean blood loss was 163.3±54.9ml(100-300ml). The average follow-up time was 15.8±2.2 months(13-20 months). 7 cases(10 segments) occurred cage subsidence, 2 of them were not placed posterior pedicle screw fixation, and 2 of them had intra-operative end plate damage. 3 cases experienced transient pain in the front of legs and 1 case lower limbs weakness, but recovered 1 week later. The clinical outcomes of all the patients improved during the follow-up. Before surgery, 1 week after surgery and at final follow-up, the mean JOA scores were 11.2±1.9, 19.4±1.3, 25.0±0.72, the mean ODI scores were (68.5±5.9)%, (45.6±5.65)%, (12.2±5.1)%, respectively. All the clinical outcomes after surgery improved significantly comparing with those before surgery(P<0.01). At the three time points, the mean IDH was 9.16±2.7mm, 12.7±2.6mm, 10.8±3.0mm, the mean IFH was 16.9±3.7mm, 20.7±3.7mm, 18.1±4.2mm. The radiographic outcomes at 1 week after surgery improved significantly comparing with those before surgery(P<0.01), and the outcomes of final follow-up did not improved significantly comparing with those before surgery(P>0.05). Conclusions: Oblique lumber interbody fusion has satisfying and safe short-term outcomes in lumbar degenerative disease. Further follow-up and research is needed to access the long-term outcomes.
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