LI Zhehuang,WEI Feng,XU Nanfang.Evaluation of dilute betadine immersion in reducing postoperative surgical site infection after spine surgery[J].Chinese Journal of Spine and Spinal Cord,2016,(3):244-248.
Evaluation of dilute betadine immersion in reducing postoperative surgical site infection after spine surgery
Received:November 07, 2015  Revised:December 11, 2015
English Keywords:Spine surgery  Surgery site infection  Betadine
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Author NameAffiliation
LI Zhehuang Orthopedics Department of Peking University Third Hospital, Beijing, 100191, China 
WEI Feng 北京大学第三医院骨科 100191 北京市 
XU Nanfang 北京大学第三医院骨科 100191 北京市 
刘忠军  
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English Abstract:
  【Abstract】 Objectives: To evaluate the role of intra-operative 1% dilute betadine solution immersion in prevention of surgical site infection(SSI) of spinal surgery. Methods: The study included 706 adult patients from January 2010 to December 2014 who underwent spine surgery by the same surgeon. The surgery such as vertebroplasty, debridement, Halo-Vest placement, percutaneous endoscopic spinal surgery, instrumentation removal were excluded. 1000-1500ml normal saline irrigation was used before wound closure in 319 patients from January 2010 to December 2012 as group 1. A two-minute 1% betadine solution immersion and a normal saline irrigation were used for the 387 patients from January 2013 to December 2014 as group 2. Results: 9 SSI occured in group 1(2.8%) including 2 superficial infections(0.6%) and 7 deep infections(2.3%). Only 1 superficial infection(0.2%) occured in group 2. The differences of total infection rate(P=0.009) and deep infection rate(P=0.009) between the two groups were statistically significant. Most variables between the two groups were comparable. Conclusions: Dilute betadine irrigation is an effective, simple and cheap way to reduce surgical site infection rate after spinal surgery. A higher-level and larger-scale study to explore the accurate efficacy and an optimal operation standard is still needed.
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