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| PAN Fumin,WANG Shanjin,MA Bin.The relationship between type Ⅱ diabetes mellitus and lumbar disc degeneration[J].Chinese Journal of Spine and Spinal Cord,2015,(12):1079-1082. |
| The relationship between type Ⅱ diabetes mellitus and lumbar disc degeneration |
| Received:May 26, 2015 Revised:October 29, 2015 |
| English Keywords:Lumbar discs degeneration Diabetes mellitus Type Ⅱ Magnetic resonance imaging Pfirrmann grading system |
| Fund:国家自然科学基金青年基金资助项目（编号：81201418）；同济大学青年优秀人才培养行动计划资助项目（编号：2013KJ075）；浦东新区卫生系统重点学科建设资助项目（编号：PWZx2014-02） |
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| English Abstract: |
| 【Abstract】 Objectives: To observe the relationship between type Ⅱ diabetes mellitus(DM) and lumbar discs degeneration(LDD). Methods: During 2013, 390 adults with low back pain in our spine clinic were chosen according to the including criterion. All the patients were divided into the following three groups: non-DM group(n=123), well-controlled DM group(group A; n=140) and badly-controlled DM group(group B; n=127). In group A, 68 patients were with DM duration ≤10 years(group A1), and 72 patients with DM duration ＞10 years(group A2); in group B, there were 60 patients with DM duration ≤10 years(group B1) and 67 patients with DM duration ＞10 years(group B2). Severity of LDD was evaluated by the five-level Pfirrmann grading system. SPSS 19.0 was used to analyze the relationship between type Ⅱ DM and LDD. Results: The data of each group obeying the normal distribution(P＞0.05) and demographic data showed no different between two groups(P＞0.05). From L1/2 to L5/S1, the average Pfirrmann scores between group A1 and non-DM patients showed no difference(P＞0.05); group A2, B1 and B2 showed higher average Pfirrmann scores than non-DM patients(P＜0.05). Group A2 and B2 showed higher average Pfirrmann scores than group A1 and B1(P＜0.05). Group B1 and B2 showed higher average Pfirrmann scores than group A1 and A2(P＜0.05). From L1/2 to L5/S1, the severity of LDD was highly related to DM duration both in group A and B(P＜0.05). Conclusions: DM duration ＞10 years and bad control of DM are the risk factors of LDD, and severity of LDD is highly related to DM duration. |
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