ZOU Haibo,SHENG Houfu,LI Zhongshi.The clinical outcomes of minimally invasive unilateral or bilateral TLIF for lumbar degenerative disease[J].Chinese Journal of Spine and Spinal Cord,2013,(12):1086-1091.
The clinical outcomes of minimally invasive unilateral or bilateral TLIF for lumbar degenerative disease
Received:May 17, 2013  Revised:July 13, 2013
English Keywords:Lumbar vertebrae  Degenerative disease  Surgical procedures  Minimally invasive
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Author NameAffiliation
ZOU Haibo Spine Division of Orthopaedic Department, China-Japan Friendship Hospital, Beijing, 100029, China 
SHENG Houfu 北京中日友好医院脊柱外科 100029 北京市 
LI Zhongshi 北京中日友好医院脊柱外科 100029 北京市 
陈 栋  
赵景鑫  
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English Abstract:
  【Abstract】 Objectives: To evaluate the clinical outcomes of minimally invasive unilateral or bilateral transforaminal lumbar interbody fusion(TLIF) for lumbar degenerative disease. Methods: From January 2011 to November 2012, 52 patients with single-level lumbar degeneration disease were treated through mini-TLIF for unilateral(31 cases) and bilateral(21 cases) pedicle screw fixation assisted by Mast Quadrant. The average age of patients was 52.9 years(ranged, 30-77), including 27 males and 25 females. The operation time, intraoperative blood loss, postoperative hospital stay and surgical cost were recorded. The pre- and post-operative clinical outcomes were assessed by visual analogue scale(VAS) and Oswestry disability index(ODI). The pre- and post-operative radiologic parameters were compared which included the sagittal Cobb angle and the disc height. Results: The mean follow-up time was 12 months(ranged, 3-18). There were significant differences between two groups on operation time, hospital stay and surgical cost(P<0.01). The ODI of all patients decreased from (67.67±18.59)% to (25.58±20.80)%. The VAS improved from 7.42±2.48 to 2.09±2.47 for low back pain and from 8.04±1.22 to 2.46±2.07 for leg pain. There were significant differences with respect to the improvement rate of ODI and VAS for all patients(P<0.001). There was no statistical deference between pre- and post-operative ODI and VAS scores for each group(P>0.05). The postoperative radiologic indexes of all patients were higher than the preoperative ones(P<0.05). But no statistical difference of radiologic indexes between preoperation and final follow-up for each group was noted(P>0.05). Except one patient with bilateral fixation adjusted pedicle screw because of leg pain after operation, at final follow-up, all the patients achieved radiographic fusion without instrument failure and other complications. Conclusions: Mini-TLIF through Mast Quadrant regardless of unilateral or bilateral fixation is reliable for degenerative lumbar disease. Unilateral fixation is of-less surgical time, less duration of postoperative hospital and less medical costs.
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