| Home | Magazines | Editorial Board | Instruction | Subscribe Guide | Archive | Advertising | Template | Guestbook | Help |
| ZHAO Jian,GUO Zhiping,WANG Linfeng.Association between apparent diffusion coefficient and degeneration grading of intervertebral disc in patients with low back pain by using diffusion weighted image at 3.0 Tesla MR[J].Chinese Journal of Spine and Spinal Cord,2013,(12):1074-1078. |
| Association between apparent diffusion coefficient and degeneration grading of intervertebral disc in patients with low back pain by using diffusion weighted image at 3.0 Tesla MR |
| Received:August 09, 2013 Revised:October 23, 2013 |
| English Keywords:Low back pain Magnetic resonance imaging Diffusion weighted imaging Apparent diffusion coefficient Lumbra intervertebral disc Degeneration |
| Fund:河北省自然科学基金资助项目（编号：C2011206153) |
|
| Hits: 3056 |
| Download times: 2158 |
| English Abstract: |
| 【Abstract】 Objectives: To assess the correlation between apparent diffusion coefficient(ADC) of lumbar intervertebral disc on diffusion weighted image(DWI) and degeneration grading of intervertebral disc in patients with low back pain. Methods: From June to November 2012, T2 weighted image(T2WI) and DWI sequence of lumbar spine were performed on 60 patients with low back pain by using a 3.0T MR scanner. There were 30 males and 30 females, with the age ranging at 19-66 years(average, 42.5±11.9 years). The Pfirrmann grading was performed on T2WI sequence. ADC values of intervertebral discs were measured in middle slice of sagittal ADC mapping. The correlation between ADC values and Pfirrmann grading was tested by Spearman analysis. One-way ANOVE was used to test the difference on ADC values among various Pfirrmann grading of intervertebral discs. LDS method was used to furtherly test if the difference was significant. Results: Pfirrmann grading of intervertebral discs in patients with lower back pain was as following: grading Ⅰ, 45 discs (15%); grading Ⅱ, 74 discs(24.7%); grading Ⅲ, 74 discs(24.7%); grading Ⅳ, 113 discs(37.7%); grading Ⅴ, 7 discs(2.3%). The ADC value of Pfirrmann grading Ⅰ, Ⅱ, Ⅲ, Ⅳ, Ⅴ was 1.73±0.21, 1.74±0.15, 1.62±0.24, 1.23±0.37, 0.81±0.32(10-3mm2/s), respectively. Significant difference on ADC values was found among various Pfirrmann grading levels, with F=56.9, P=0.000. While further test by using LDS method showed no significant difference on ADC values between Pfirrmann grading Ⅰ and grading Ⅱ(P>0.05). Significant differences on ADC values were found between any two levels of Pfirrmann grading Ⅲ, grading Ⅳ, and grading Ⅴ(P<0.05). Negative correlation was found between ADC values and Pfirrmann grading(r=-0.642, P=0.000). Conclusions: Negative correlation between ADC values and degeneration grading of lumbar intervertebral discs in patients with low back pain exists by using 3.0T MR DWI. |
| View Full Text View/Add Comment Download reader |
| Close |
|
|
|
|
|