CHEN Zhonghui,SUN Xu,QIU Yong.Radiographic characteristics of scoliosis combined with arthrogryposis multiplex congenita[J].Chinese Journal of Spine and Spinal Cord,2013,(12):1057-1062.
Radiographic characteristics of scoliosis combined with arthrogryposis multiplex congenita
Received:August 17, 2013  Revised:September 29, 2013
English Keywords:Arthrogryposis multiplex congenita  Scoliosis  Radiographic characteristics
Fund:国家自然科学基金面上项目(编号:81171767,81372010),国家临床重点专科骨科建设项目
Author NameAffiliation
CHEN Zhonghui Spine Surgery, Drum Tower Hospital, Nanjing University Medical School, Nanjing, 210008, China 
SUN Xu 南京大学医学院附属鼓楼医院脊柱外科 210008 南京市 
QIU Yong 南京大学医学院附属鼓楼医院脊柱外科 210008 南京市 
王 斌  
江 龙  
汪 舟  
徐磊磊  
朱泽章  
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English Abstract:
  【Abstract】 Objectives: To investigate the radiographic characteristics of scoliosis combined with arthrogryposis multiplex congenita(AMC). Methods: From November 2001 to April 2013, a total of 41 AMC patients who visited our hospital initially for scoliosis, including 21 males and 20 females with the age ranging from 4 to 28 years(average, 15.6±3.9 years), was reviewed retrospectively. Curve pattern and levels of involved vertebrae were recorded. The following parameters were measured: the Cobb angle of main curve, flexibility, pelvic obliquity, thoracic kyphosis(TK) and lumbar lordosis(LL). Correlation analysis was performed between pelvic obliquity and coronal curve. Results: 7 cases were associated with congenital vertebral anomalies. Single curve was found in 37 cases(90%), among whom there were 21 with a single thoracic curve and 16 with a single thoracolumbar curve. 4 cases(10%) had thoracic and lumbar curves. The main curve averagely spanned 9±1 levels. The Cobb angle averaged 80°±29°, and the flexibility averaged(20±11)%. There were 22 cases(54%) with the pelvic obliquity ranging from 7° to 27°(average, 16°±5°). Significant positive correlation was found between pelvic obliquity and the Cobb angle of main curve(r=0.612, P<0.05). On the sagittal plane, 20 cases(49%) had thoracic lordosis, 5 cases(12%) had decreased thoracic kyphosis, and 24 cases(59%) had lumbar hyperlordosis. Conclusions: Single curve pattern is predominantly seen in scoliosis with AMC. The curves are always rigid. Congenital vertebral anomalies may also be detected in some patients. Single curve with rigid flexibility and pelvic obliquity on the coronal plane, and thoracic and lumbar hyperlordosis on the sagittal plane are the typical features of scoliosis in AMC. Pelvic obliquity strongly correlates with severity of scol?鄄iosis.
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