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| YU Liang,XU Rongming,MA Weihu.Meta-analysis of outcomes of transforaminal lumbar interbody fusion versus posterior lumbar interbody fusion for degenerative lumbar diseases[J].Chinese Journal of Spine and Spinal Cord,2013,(10):886-890. |
| Meta-analysis of outcomes of transforaminal lumbar interbody fusion versus posterior lumbar interbody fusion for degenerative lumbar diseases |
| Received:February 01, 2013 Revised:June 10, 2013 |
| English Keywords:Transforaminal lumbar interbody fusion Posterior lumbar interbody fusion Meta-analysis |
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| English Abstract: |
| 【Abstract】 Objectives: To make a Meta-analysis of comparative studies in an attempt to assess clinical outcomes and complication rates after transforaminal lumbar interbody fusion(TLIF) versus posterior lumbar interbody fusion(PLIF) for degenerative lumbar diseases. Methods: By searching Medline, Ovid, CBM, CNKI and VIP, etc, the published articles about studies of TLIF versus PLIF for degenerative lumbar diseases were collected. The data included: operation time, blood loss, hospital stay, visual analogue score(VAS), Oswestry disability index(ODI) and complications. Review Manager 5.1 software was used for data analysis. Results: One randomized controlled trials and eight cohort studies including 981 patients were included in the Meta-analysis(457 patients for TLIF, 524 patients for PLIF). Postoperative outcome(P=0.27), operation time(P=0.07), blood loss(P=0.002), hospital stay(P=0.02) showed better results of TLIF than PLIF, VAS(P=0.61) and ODI(P=0.24) showed no significant difference between two groups; TLIF had less total complications(P<0.0001), nerve injury(P=0.001), dura injury(P=0.04) than PLIF, while cerebrospinal fluid leakage(P=0.25), screw loosening(P=0.14), internal fixation fail(P=0.86), nonunion(P=0.41) and infection(P=0.51) showed no differences between 2 groups. Conclusions: TLIF has similar outcome with PLIF, however, the former has less blood loss, hospital stay and complications rate than the latter, especially for nerve and dura injury, which indicates safety and effectiveness for TLIF. |
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