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| FENG Fan,QIAN Bangping,QIU Yong.Correlation and clinical significance of the decreased cervical mobility in ankylosing spondylitis patient with thoracolumbar kyphosis[J].Chinese Journal of Spine and Spinal Cord,2013,(7):617-621. |
| Correlation and clinical significance of the decreased cervical mobility in ankylosing spondylitis patient with thoracolumbar kyphosis |
| Received:December 27, 2012 Revised:February 08, 2013 |
| English Keywords:Ankylosing spondylitis Kyphosis Cervical range of motion |
| Fund:南京市医学发展科技项目（编号：YKK09100）；江苏省自然科学基金资助项目（编号：BK 2011092） |
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| English Abstract: |
| 【Abstract】 Objectives: To investigate the risk factors and its clinical significance of limited cervical range of motion in ankylosing spondylitis(AS) patients with thoracolumbar kyphosis. Methods: From May 2012 to October 2012, 38 AS patients(with complete medical records) from the 51 consecutive AS patients with thoracolumbar kyphosis in our hospital were enrolled. There were 36 males and 2 females, with an average age of 32.6 years(range, 17-53 years). The clinical data consisted of age, disease course, erythrocyte sedimentation rate(ESR), C-reaction protein(CRP). The radiographic parameters were composed by global kyphosis(GK), cervical mSASSS(the modified Stokes ankylosing spondylitis spinal score), cervical curve and C2-C7 SVA. The quality of life questionnaires consisted of bath ankylosing spondylitis disease activity index(BASDAI), bath ankylosing spondylitis functional index(BASFI) and Oswestry disability index(ODI). According to the value of cervical range of motion(CROM), the subjects were divided into two groups: group A, CROM >40°; group B, CROM <20°. The independent t-test was used to compare the parameters between the two groups. Furthermore, the Pearson correlation test was performed to investigate the risk factors correlated with CROM. Results: In group A, there were 16 patients with an average CROM of 65.8°±14.3°(41°-92°), while 17 patients in group B with an average CROM of 9.2°±6.6°(1°-19°). With respect to the disease course, BASFI, GK, mSASSS, cervical curve and C2-C7 SVA, significant differences were found between two groups(P<0.05). However, the age, ODI, BASDAI, ESR or CRP showed no significant difference between group A and B(P>0.05). There were remarkable correlations between CROM and disease course, mSASSS, cervical curve, C2-C7 SVA and BASFI(r=-0.524, -0.895, 0.494, -0.813, and -0.501 respectively, P<0.05). Especially, there was no significant correlation between GK and CROM(r=-0.275, P=0.122). Conclusions: Longer disease course and cervical structural damage are high risk factors of CROM in AS patients with thoracolumbar kyphosis. AS patients′ quality of life is severely affected by the limited cervical range of motion. |
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