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| LIU Fajing,DU Wei,SHEN Yong.Surgical outcome of percutaneous kyphoplasty for vertebral compression fracture with different bone mineral density[J].Chinese Journal of Spine and Spinal Cord,2012,(4):324-329. |
| Surgical outcome of percutaneous kyphoplasty for vertebral compression fracture with different bone mineral density |
| Received:November 20, 2011 Revised:February 24, 2012 |
| English Keywords:Percutaneous kyphoplasty Bone mineral density Vertebral compression fractures Clinical therapeutic |
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| English Abstract: |
| 【Abstract】 Objectives: To investigate the clinical variation of percutaneous kyphoplasty(PKP) in treating vertebral compression fracture with different bone mineral density(BMD). Methods: Between March 2008 and November 2009, 76 patients (32 males and 44 females, average age: 63.1 years, range: 50-81 years) suffering from single level of vertebral compression fracture and undergoing PKP in our institute were retrospectively reviewed. The bone mineral density of lumbar was measured by dual-energy X-ray absorptiometry. According to the T-score, the patients were divided into 3 groups: group A(osteoporosis group, 33 cases), group B (bone loss group, 26 cases) and group C (normal bone group, 17 cases). The visual analogue scale(VAS), Oswesty disability index (ODI), vertebral height restoration and complications were used to evaluate the surgical outcome. Results: All patients reached quick back pain relief without neurological deficit and instrument failure. All patients had a follow-up of 1.5-2.7 years. Compared with pre-operation, the VAS score and ODI decreased significantly at 3 days after operation and final follow-up in 3 groups(P＜0.05), but no inter-group significant difference was noted(P＞0.05). When comparing the index of vertebral average height and local Cobb′s angle pre- and post-operation, each group had a significant recovery(P＜0.05). Group A had a higher striking vertebral height restoration rate(65.3%) than group B(57.9%) and C(54.2%) (P＜0.05). A total of 8 patients had bone cement leakage during operation, that 2 in group A(6.06%), 3 in group B(11.54%) and 3 in group C(17.65%), there was no statistical difference among the 3 groups at cement leakage rate. One patient was complicated with pulmonary embolism due to cement leakage in group A, which was resolved after correspondent intervention. During the follow-up, 2 adjacent vertebral fractures were found in group A, both of them recovered after an extra PKP treatment. Conclusions: PKP can provide an effective and safe therapeutic effect for vertebral compression fracture with different bone mineral density. Patients who have a lower BMD will get a better vertebral height restoration and Cobb′s angle rectification. However, patients who have the complication of osteoporosis should pay more attention to the adjacent vertebral fracture after the PKP procedure. |
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