YAN Taiqiang,GUO Wei,YANG Rongli.Bone cement vertebroplasty for spinal metastasis tumor[J].Chinese Journal of Spine and Spinal Cord,2012,(4):318-323.
Bone cement vertebroplasty for spinal metastasis tumor
Received:July 19, 2011  Revised:September 26, 2011
English Keywords:Spine  Neoplasm metastasis  Vertebroplasty open surgery.
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Author NameAffiliation
YAN Taiqiang Orthopaedic Oncology Department, People′s Hospital, Peking University, Beijing 100044, China 
GUO Wei 北京大学人民医院骨肿瘤科 100044 北京市 
YANG Rongli 北京大学人民医院骨肿瘤科 100044 北京市 
董 森  
唐 顺  
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English Abstract:
  【Abstract】 Objective: To evaluate the therapeutic effects of bone cement vertebroplasty for spinal metastasis tumor. Method: A retrospective review(from November 2000 to June 2011) was conducted on 155 consecutive patients(mean age, 63.5 years old), a total of 251 vertebrae were involved. Percutaneous vertebroplasty or surgical decompression combined with posterior instrumentation was performed in 181 vertebrae(110 patients) and 70 vertebrae(45 patients) respectively. All patients complained of severe back pain, with or without neurological deficits of lower limbs preoperatively. The patients′ demographic data, visual analog scale(VAS), improvement rate, outcome and complications were evaluated. Result: The mean preoperative VAS score was 7.6, which decreased dramatically to 2.6 postoperatively(P<0.01). The neurological dysfunction was improved after operation. 2 weeks after operation, all 39 patients except 2 cases suffering from neurological deficit had Frankel scale improved at least 1 level. 18 cases had IV ECOG scale, of these, 15 cases had 3 levels of improvement; 92 cases had III ECOG scale, of these, 63 cases had 2 levels of improvement; 45 cases had II ECOG scale, of these, 13 cases had 1 levels of improvement. The average bone cement volumn infilled was 4ml(range, 3~7ml). Bone cement leakage was noted in 108 vertebrae(43%, 108/251). The mean follow-up was 20 months(range, 3-36 months). 122 patients died of original diseases, while the other 33 remained alive. Conclusion: Vertebroplasty is safe, minimal invasive and reliable which can obviate anterior open surgery.
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