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| YANG Xi,SONG Yueming,LIU Hao.Preliminary outcome of anterior decompression，n-HA/PA66 implantation and fusion for thoracolumbar burst fracture[J].Chinese Journal of Spine and Spinal Cord,2011,(11):885-889. |
| Preliminary outcome of anterior decompression，n-HA/PA66 implantation and fusion for thoracolumbar burst fracture |
| Received:May 20, 2011 Revised:July 20, 2011 |
| English Keywords:Ｎano-hydroxyapatite/polyamide 66 Ｖertebral supporter Ｔhoracolumbar Ｂrust fracture Ａnterior surgery |
| Fund:基金项目：国家科技支撑计划课题———活性纳米复合生物材料制品手术示范与临床应用（2007BAE131304） |
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| English Abstract: |
| 【Abstract】 Objective：To evaluate the short-term efficacy of the nano-hydroxyapatite/polyamide 66（n-HA/PA66） implantation following anterior decompression for thoracolumbar burst fracture.Method：In this study，214 patients suffering thoracolumbar brust fracture received anterior decompression，n-HA/PA66 implantation and instrumentation from September 2007 to October 2010.There were 153 males and 61 females with the average age of 37.6 years（19-58 years）.The neurological function，X-ray and 3-dimensions CT（3D-CT） scans at preoperative，1-week and ｆｉｎａｌ follow-up were reviewed retrospectively.The neurological function wａｓ analyzd according to Frankel criteria。Ｔhe Cobb angle and vertebra height and fusion status were reviewed.Result：188 patients were followed up for an average of 17.8m（6-36 months）.The preoperative neurological function included 20 Frankel A，38 B，59 C，47 D，24 E，and those at final follow-up included 17 A，9 B，20 C，46 D and 96 E.The mean Cobb angle ａｔ preoperatiｏｎ，1-week after operation and final follow-up was 17.5°，5.4° and 5.7°respectively．Ｔhe means height of fractured vertebral body was 97.9mm before surgery，109.0mm 1 week after surgery and 108.4mm at final follow-up with the mean loss of correction of 0.6mm.9 cases（4.8%）were complicated with prosthesis subsidence（loss of height≥2mm）.All cases had bony fusion rate of 96.3%，ａｎｄ no deep infection or instrument failure was noted.Conclusion：The n-HA/PA66 implantation following anterior decompression is effective and reliable for thoracolumbar brust fracture，which has lower rate of subsidence and higher rate of bony union，and can be used for anterior vertebra reconstruction. |
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