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ZHU Jiajun,TU Guanjun.Kyphoplasty versus vertebroplasty for osteoporotic vertebral compression fracture:a Meta analysis[J].Chinese Journal of Spine and Spinal Cord,2011,(10):848-852. |
Kyphoplasty versus vertebroplasty for osteoporotic vertebral compression fracture:a Meta analysis |
Received:March 28, 2011 Revised:May 04, 2011 |
English Keywords:Kyphoplasty Vertebroplasty Osteoporosis Vertebral compression fracture Meta analysis |
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English Abstract: |
【Abstract】 Objective:To evaluate the efficacy and safety of kyphoplasty versus vertebroplasty for osteoporotic vertebral compression fracture(OVCF).Method:A systematic computer-based search(from Jan 1997 to Jan 2011)of Ovid medline,Web of science,EMbase,Cochrane central register of controlled trial(Issue 1 of 4,2011) and manual search of related journals were performed for collecting controlled trials on kyphoplasty and vertebroplasty for OVSF.The included trials were screened based on the inclusion and exclusion criteria.The quality of included trials was evaluated.RevMan 5.0.25 software was used for data analysis.Result:9 non-randomized prospective and controlled trials and 1 randomized controlled trial involving a total of 749 patients were included.PKP and PVP groups reached remarkable pain relief,and the former had more pain relief than the latter in 1 year(P<0.05),while this difference was more significant over 1 year(P<0.05).Two groups had severe improvement of disability,but no inter-group difference was noted(P>0.05).Majority of literatures showed PVP was superior than PKP in restoring vertebral height and deformity correction(P<0.05),however some papers considered no difference existed between 2 groups(P>0.05);2 groups had similar effect on life quality improvement(P>0.05),however as for complications,PKP group had fewer complications noted than PVP group(P<0.05).Conclusion:Kyphoplasty is superior in pain relief,correction of deformity and height restoration than vertebroplasty,nevertheless PVP can not be denied. |
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