SUN Yu,ZHAO Yanbin,ZHOU Feifei.Effect of cervical disc arthroplasty on adjacent segment degeneration[J].Chinese Journal of Spine and Spinal Cord,2011,(6):474-479.
Effect of cervical disc arthroplasty on adjacent segment degeneration
Received:December 26, 2011  Revised:February 21, 2011
English Keywords:Cervical disc replacement  Adjacent segment degeneration  Adjacent segment disease
Fund:
Author NameAffiliation
SUN Yu Department of Orthopedic SurgeryPeking University Third HospitalBeijing100191China 
ZHAO Yanbin 北京大学第三医院骨科 100191 北京市 
ZHOU Feifei 北京大学第三医院骨科 100191 北京市 
张凤山  
潘胜发  
周 方  
刘忠军  
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English Abstract:
  【Abstract】 Objective:To investigate the adjacent segment degeneration after single level cervical disc arthroplasty.Method:Patients received single level cervical arthroplasty in our institute were reviewed retrospectively.Up to October 2010,a total of 80 patients gained at least 20 months′ follow-up.There were 8 cases of C3/4,15 C4/5,49 C5/6 and 8 C6/7.41 patents received Bryan Disc cervical prosthesis and 39 received ProDisc-C prosthesis.Adjacent segment degeneration was evaluated on X-ray and magnetic resonance imaging(MRI) at preoperative and final follow-up.X-ray based adjacent segment degeneration included the presence of any of the following parameters:narrowing of disc space>10%,new anterior or/and extended osteophyte formation,calcification of anterior longitudinal ligament.Cervical disc degeneration was evaluated according to Miyazaki′s grading system based on T2-weighted MRI.Result:The mean follow-up period was 38 months(range,20-64 months).Of 160 segments at final follow-up,8 distal adjacent segments were excluded due to unavailability of X-ray,adjacent segment degeneration was observed in 21 of 152 segments(13.8%) based on X-ray findings.The rate of adjacent segment degeneration for Bryan disc group was 10.0%,which was lower than that of ProDisc-C group(18.1%).47 patients gained MRI follow-up,and adjacent segment degeneration was observed in 14 of 94 segments(14.9%).The rate of MRI-based adjacent segment degeneration for Bryan Disc group was 12.5%,which was also lower than that of ProDisc-C group(22.7%).No adjacent segment disease developed at final follow-up.Conclusion:Less than 15% cases develop adjacent segment degeneration 38 months after cervical disc arthroplasty,and the effect may vary between different prosthesis.
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