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| LI Jigang,YANG Huilin,WANG Genlin.Diagnostic value of vertebral biopsy during percutaneous vertebroplasty or percutaneous kyphoplasty for vertebral compression fractures[J].Chinese Journal of Spine and Spinal Cord,2010,20(11):945-949. |
| Diagnostic value of vertebral biopsy during percutaneous vertebroplasty or percutaneous kyphoplasty for vertebral compression fractures |
| Received:July 12, 2010 Revised:September 02, 2010 |
| English Keywords:Vertebral compression fracture Biopsy Percutaneous vertebroplasty Percutaneous kyphoplasty |
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| English Abstract: |
| 【Abstract】 Objective：To discuss the diagnostic value of vertebral biopsy during percutaneous vertebroplasty（PVP） or percutaneous kyphoplasty（PKP） for osteoporotic vertebral compression fractures（OVCFs）.Method：From January 2003 to December 2009，261 vertebral bodies from 209 patients with vertebral compression fractures underwent intraoperative biopsy during either PVP or PKP.There were 165 females and 44 males with the average patient age at surgery of 68 years old（range，36-93 years old）.The diagnosis was osteoporostic vertebral compression fracture in 185 patients，and pathological fracture in 24 patients.All 261 vertebrae had biopsies.Histologic/immunohistochemical tests were performed on each speimens.Result：No surgery related complications were noted in all patients.The biopsy results from 183 patients presumed with OVCFs showed consistence.While for 24 patients having history of malignancy，only 14 showed consistency with their primary diagnosis，and the other 10 patients were determined to have compression fracture despite of their tumor history.2 patients presumed of OVCFs were found malignant，1 multiple myeloma and 1 metastatic carcinoma.The rate of misdiagnose to compression fracture in our study was 1.1%（2/185）.Conclusion：Vertebral body biopsy prior to vertebral augmentation does not increase the risk，on the contrary，it helps to the final pathological identification.As a result，it should be performed routinely. |
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