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| ZANG Jiacheng,MA Xinlong,MA Jianxiong.Meta-analysis of microdiscectomy versus standard discectomy in the treatment of Lumbar Disc Herniation[J].Chinese Journal of Spine and Spinal Cord,2010,20(11):938-944. |
| Meta-analysis of microdiscectomy versus standard discectomy in the treatment of Lumbar Disc Herniation |
| Received:June 28, 2010 Revised:August 17, 2010 |
| English Keywords:Lumbar disc herniation Microdiscectomy Standard discectomy Meta-analysis |
| Fund:基金项目：天津市科委应用基础与前沿技术研究计划重点项目（09JCZDJC19600）；天津市卫生局科技基金（09kR08）；天津市卫生局科技基金（06kz48） |
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| English Abstract: |
| 【Abstract】 Objective：To assess the effectiveness of microdiscectomy versus standard discectomy for lumbar disc herniation.Method：A computer-based online search of Medline（1977 to May，2010），EMBASE（1977 to May，2010），Cochrane Controlled Clinical Trials Register（1th Quarter 2010），Current Controlled Trials（２００３ to May，2010）.The China Biological Medicine Database（1984 to May，2010），and several hand searched related journals ｗｅｒｅ ｐｅｒｆｏｒｍｅｄ.Ｔｈｅ randomized ａｎｄ controlled trials of microdiscectomy versus standard discectomy ｗｅｒｅ ｃｏｌｌｅｃｔｅｄ.The included trials were screened out ｓｔｒｉｃｔｌｙ ｂａｓｅｄ ｏｎ the criterion of inclusion and exclusion.The quality of included trials was evaluated.Data were extracted by two reviewers independently.RevMan 5.0 was used for data analysis.Result：Nine studies involving 1109 patients were included.There were 654 patients with microdiscectomy and 455 standard discectomies.The results of Meta-analysis indicated that statistically significant difference were observed between two approaches with respect to the mean operation time（P＜0.0５），blｏｏd ｌｏｓｓ（P＜0.0１），ａｎｄ postoperative VAS ｓｃｏｒｅ of back pain（P<0.01）.Ｎｏ difference ｗｉｔｈ ｒｅｇａｒｄ ｔｏ the inpatient stay，complication，reoperation rate，postoperative VAS of leg pain and JOA score ｗｅｒｅ ｎｏｔｅｄ.Conclusion：Both microdiscectomy and standard discectomy are effective treatment for LDH.Ｃompareｄ with standard open discectomy，microdiscectomy ｉｓ ｂｅｔｔｅｒ due to ｌｅｓｓ ｂｌｏｏｄ ｌｏｓｓ ａｎｄ better ｂａｃｋ ｐａｉｎ relief，but ｌｏｎｇｅｒ operation time.There is no significant difference in overall effectiveness. |
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