HUANG Hui,SHOU Kangquan,LI Jian.Application of ozone on autoimmunity of patients with lumbar prolapsed disc[J].Chinese Journal of Spine and Spinal Cord,2010,20(11):935-937.
Application of ozone on autoimmunity of patients with lumbar prolapsed disc
Received:July 05, 2010  Revised:September 03, 2010
English Keywords:Lumbar disc herniation  Medical ozone  Humoral immunity
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Author NameAffiliation
HUANG Hui Department of OrthopaedicsGezhouba Dam Central HospitalYichang443002China 
SHOU Kangquan  
LI Jian  
付纳新  
赵 伟  
罗 刚  
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English Abstract:
  【Abstract】 Objective:To investigate the use of ozone on autoimmunity of patients with lumbar prolapsed disc.Method:50 cases with lumbar prolapsed disc and 50 healthy adults were collected.The concentration levels of immunoglobulin G and M in peripheral blood by immunoturbidimetry between patients and healthy ones were compared,then lumbar disc herniation(LDH) patients underwent percutaneous intradiscal ozone-injection(PIOI),and the concentration levels of immunoglobulin G and M of these patients between pre-operation and post-operation were compared.Result:The immunoglobulin G and M level in peripheral blood of LDH patients were 16.04±2.58g/L and 1.79±0.45g/L respectively.Both were significantly higher than that of the healthy adults(13.33±2.67g/L and 0.89±0.34g/L)(P<0.01).After operation,the levels were 14.15±2.43g/L and 1.43±0.39g/L for immunoglobulin G and M level respectively,both were significantly lower than those of preoperation(P<0.01).Conclusion:Ozone for medical use can inhibit the auotoimmunity of patients with lumbar prolapsed disc,which remains one of the mechanisms for managing LDH.
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