GUO Zhao,ZHAO Qiang,DING Wenyuan.Correlative study of degenerative lumbar scoliosis and osteoporosis[J].Chinese Journal of Spine and Spinal Cord,2010,20(7):558-561.
Correlative study of degenerative lumbar scoliosis and osteoporosis
Received:March 03, 2010  Revised:April 26, 2010
English Keywords:Osteoporosis  Degenerative lumbar scoliosis  Dual-energy x-ray absorptiometry  Correlation
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Author NameAffiliation
GUO Zhao Spine Servicethe Third Hospital of Hebei Medical UniversityShijiazhuang050051China 
ZHAO Qiang 河北省保定市第一医院神经外科 071000 
DING Wenyuan 河北医科大学第三医院脊柱外科 050051 石家庄市 
申 勇 河北医科大学第三医院脊柱外科 050051 石家庄市 
陈宏亮 河北医科大学第三医院脊柱外科 050051 石家庄市 
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English Abstract:
  【Abstract】 Objective:To investigate the correlation between degenerative scoliosis and osteoporosis.Method: From Jan.2004 to Jun.2009,69 patients diagnosed with degenerative scoliosis from out-patient and wards were included in the group.There were 6 males and 63 females with an average age of 69.3 years(range,from 51 to 82 years).All the patients underwent X-Ray and MRI examines to comfirm the diagnosis,and Cobb angle was recorded respectively.Control group had 50 cases without scoliosis,including 37 spinal stenosis,8 lumbar disc herniation,4 spondylolisthesis and 1 lumbar spinal tumor.The bone density of lumbar,femoral neck, trochanter,Ward′s triangle regions was measured with dual-energy x-ray absorptiometry.Observe the T-scores of different ages and Cobb angles were observed,to analyze their correlations.Result:Of the 69 cases with degenerative scoliosis,the average T-score was -2.8±1.9(range,from -0.9 to -4.7),52 cases combined with osteoporosis,14 cases combined with osteopenia,the average T-score in the control group was -1.2±1.6(range,from 0.4 to -2.8).Significant difference was found among the mean t-scores of lumbar and proximal femoral regions of the groups(P<0.05).According to the comparision of T-score in different ages and Cobb angles,the T-score existed a positive correlation with age,and zero correlation with Cobb angle.Conclusion:Osteoporosis is a risk factor for degenerative scoliosis,there exists a significant correlation.The severity of osteoporosis doesn′t correlate with curve magnitude,but increases with the increasing of age.
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