陈柏龄,谢登辉,黎艺强,庄新明,杨晓曦,于滨生,郑召民.单侧PKP骨水泥注射过中线分布对压缩性骨折椎体两侧刚度的影响[J].中国脊柱脊髓杂志,2011,(2):118-121.
单侧PKP骨水泥注射过中线分布对压缩性骨折椎体两侧刚度的影响
中文关键词:  生物力学  经皮椎体后凸成形术  骨水泥  侧方压缩
中文摘要:
  【摘要】 目的:评价单侧椎体后凸成形术(PKP)中骨水泥注射超越椎体中线与否对椎体轴向及两侧刚度的影响。方法:3具防腐成人胸腰椎椎体标本(T4~L1)用于实验。通过MTS平台给椎体施加轴向压力,制作压缩性椎体骨折模型,同时进行球囊辅助下经单侧椎弓根穿刺椎体后凸成形术,根据骨水泥是否过椎体中线分为两组,骨水泥注射不过椎体中线(A组,n=9);骨水泥注射过椎体中线(B组,n=8),骨水泥注射量为椎体体积的10%。24h后放置在MTS-858材料实验平台上,给标本分别施加0~300N轴向和侧方压力载荷,记录并比较骨水泥注射术后,两组椎体轴向及两侧的刚度差异。结果:轴向压缩载荷下,A组与B组间轴向压缩刚度无显著差异(P>0.05);在椎体侧方压缩载荷下,尽管A组椎体骨水泥穿刺侧的刚度与B组间差异无显著性(P>0.05);但在非穿刺侧刚度上,B组显著高于A组,差异有显著性(P<0.05)。结论:行单侧PKP时,若骨水泥填充不过椎体中线时,则非穿刺侧刚度明显低于穿刺侧,而骨水泥填充过中线时,则两侧椎体刚度可同时得到显著强化。
Effects of cross-midline cement distribution on the stiffness of varied sites in compressive fractured vertebrae after unipedicular PKP:a biomechanical study
英文关键词:Biomechanics  Percutaneous kyphoplasty  Bone cement  Lateral compression
英文摘要:
  【Abstract】 Objective:To evaluate the effects of cross-midline cement injection on axial and bilateral vertebral stiffness of varied sites in compressive fractured vertebrae after unipedicular PKP.Method:Vertebral bodies harvested from 3 cadaver spines(T4-L1) were experimentally induced into compressive vertebral fractures models by MTS.Subsequently the specimens were stabilized using transpedicular balloon-assisted PKP(group A,n=9,unipedicular hemivertebral,non cross-midline cement injection,group B,n=8,unipedicular cross-midline cement injection) and the volume of cement filling were 10% of the vertebral body.Then the stablized vertebral bodies were subjected to axial and sided compression loads(0-300N,cycled) by MTS 24 hours later.After that,the stiffness was measured and compared between the two groups.Result:Under axial loading,the stiffness between group A and B showed no significant difference(P>0.05).While under sided compression loading,despite of no difference of stiffness in penetration side between group A and B(P>0.05),the stiffness in non-penetration side in group B increased more than that in group A(P<0.05).Conclusion:When performing unipedicular balloon-assisted kyphoplasty,cross-midline cement distribution or not will impact the side-related stiffness significantly.
投稿时间:2010-08-10  修订日期:2010-10-27
DOI:10.3969/j.issn.1004-406X.2011.2.118.3
基金项目:
作者单位
陈柏龄 中山大学附属第一医院脊柱外科 510080 广州市 
谢登辉  
黎艺强  
庄新明  
杨晓曦  
于滨生  
郑召民  
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